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Increased Impulsivity during Withdrawal from Cocaine Self-Administration: Role for ΔFosB in the Orbitofrontal Cortex

Increased impulsivity caused by addictive drugs is believed to contribute to the maintenance of addiction and has been linked to hypofunction within the orbitofrontal cortex (OFC). Recent data indicate that cocaine “self-administration” induces the transcription factor ΔFosB in the OFC that alters t...

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Detalhes bibliográficos
Main Authors: Winstanley, Catharine A., Bachtell, Ryan K., Theobald, David E.H., Laali, Samuel, Green, Thomas A., Kumar, Arvind, Chakravarty, Sumana, Self, David W., Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733325/
https://ncbi.nlm.nih.gov/pubmed/18539927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhn094
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