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β(1) integrin cytoplasmic variants differentially regulate expression of the anti-angiogenic extracellular matrix protein thrombospondin 1

The β(1) integrins play an important role in regulating cell proliferation and survival. Using siRNA or an inhibitory antibody to β(1), we show here that, in vivo, β(1) integrins are essential for prostate cancer growth. Among the five known β(1) integrin cytoplasmic variants, two are known to diffe...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Goel, Hira Lal, Moro, Loredana, Murphy-Ullrich, Joanne E., Hsieh, Chung-Cheng, Wu, Chin-Lee, Jiang, Zhong, Languino, Lucia R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779723/
https://ncbi.nlm.nih.gov/pubmed/19549894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0186
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