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β(1) integrin cytoplasmic variants differentially regulate expression of the anti-angiogenic extracellular matrix protein thrombospondin 1

The β(1) integrins play an important role in regulating cell proliferation and survival. Using siRNA or an inhibitory antibody to β(1), we show here that, in vivo, β(1) integrins are essential for prostate cancer growth. Among the five known β(1) integrin cytoplasmic variants, two are known to diffe...

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Detalhes bibliográficos
Main Authors: Goel, Hira Lal, Moro, Loredana, Murphy-Ullrich, Joanne E., Hsieh, Chung-Cheng, Wu, Chin-Lee, Jiang, Zhong, Languino, Lucia R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779723/
https://ncbi.nlm.nih.gov/pubmed/19549894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0186
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