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β(1) integrin cytoplasmic variants differentially regulate expression of the anti-angiogenic extracellular matrix protein thrombospondin 1
The β(1) integrins play an important role in regulating cell proliferation and survival. Using siRNA or an inhibitory antibody to β(1), we show here that, in vivo, β(1) integrins are essential for prostate cancer growth. Among the five known β(1) integrin cytoplasmic variants, two are known to diffe...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779723/ https://ncbi.nlm.nih.gov/pubmed/19549894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0186 |
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