Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence

Many splicing factors interact with both mRNA and pre-mRNA. The identification of these interactions has been greatly improved by the development of in vivo cross-linking immunoprecipitation. However, the output carries a strong sampling bias in favor of RNPs that form on more abundant RNA species l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Reid, Daniel C., Chang, Brian L., Gunderson, Samuel I., Alpert, Lauren, Thompson, William A., Fairbrother, William G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2009
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779669/
https://ncbi.nlm.nih.gov/pubmed/19861426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1821809
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