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Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence
Many splicing factors interact with both mRNA and pre-mRNA. The identification of these interactions has been greatly improved by the development of in vivo cross-linking immunoprecipitation. However, the output carries a strong sampling bias in favor of RNPs that form on more abundant RNA species l...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779669/ https://ncbi.nlm.nih.gov/pubmed/19861426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1821809 |
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