Aldosterone, Through Novel Signaling Proteins, Is a Fundamental Molecular Bridge Between the Genetic Defect and the Cardiac Phenotype of Hypertrophic Cardiomyopathy

BACKGROUND: Human hypertrophic cardiomyopathy (HCM), the most common cause of sudden cardiac death in the young, is characterized by cardiac hypertrophy, myocyte disarray, and interstitial fibrosis. The genetic basis of HCM is largely known; however, the molecular mediators of cardiac phenotypes are...

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Detalhes bibliográficos
Main Authors: Tsybouleva, Natalia, Zhang, Lianfeng, Chen, Suetnee, Patel, Rajnikant, Lutucuta, Silvia, Nemoto, Shintaro, DeFreitas, Gilberto, Entman, Mark, Carabello, Blase A., Roberts, Robert, Marian, A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779533/
https://ncbi.nlm.nih.gov/pubmed/14993121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000121426.43044.2B
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