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F-Box-directed CRL complex assembly and regulation by the CSN and CAND1
The COP9 signalosome (CSN) is thought to maintain the stability of cullin-RING ubiquitin ligases (CRL) by limiting the autocatalytic destruction of substrate adapters such as F-box proteins (FBPs). CAND1, a protein associated with unneddylated CUL1, was proposed to assist in this role in an as yet u...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779159/ https://ncbi.nlm.nih.gov/pubmed/19748355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.024 |
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