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Abnormal TDP-43 immunoreactivity in AD modifies clinicopathological and radiological phenotype
BACKGROUND: TAR DNA-binding protein 43 (TDP-43) is one of the major disease proteins in frontotemporal lobar degeneration with ubiquitin immunoreactivity. Approximately 1/4 of subjects with pathologically confirmed Alzheimer's disease (AD) have abnormal TDP-43 (abTDP-43) immunoreactivity. The a...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779031/ https://ncbi.nlm.nih.gov/pubmed/18401022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000304041.09418.b1 |
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