Detection of Intracellular ADAMTS13, a Secreted Zinc-metalloprotease, via Flow Cytometry

BACKGROUND: ADAMTS13 is a secreted metalloprotease that cleaves von Willebrand Factor multimers and maintains proper homeostasis. A severe deficiency in ADAMTS13 triggers a disorder known as thrombotic thrombocytopenic purpura (TTP). At present, ADAMTS13 expression levels are determined by immunoblo...

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Autori principali: S., Geetha, Allen, Courtni E., Hunt, Ryan, Plum, Elizabeth, Garfield, Susan, Friedman, Scott L., Soejima, Kenji, Sauna, Zuben E., Kimchi-Sarfaty, Chava
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778596/
https://ncbi.nlm.nih.gov/pubmed/19526483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20748
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