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Detection of Intracellular ADAMTS13, a Secreted Zinc-metalloprotease, via Flow Cytometry
BACKGROUND: ADAMTS13 is a secreted metalloprotease that cleaves von Willebrand Factor multimers and maintains proper homeostasis. A severe deficiency in ADAMTS13 triggers a disorder known as thrombotic thrombocytopenic purpura (TTP). At present, ADAMTS13 expression levels are determined by immunoblo...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778596/ https://ncbi.nlm.nih.gov/pubmed/19526483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20748 |
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