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Mutant p53 mediates survival of breast cancer cells
BACKGROUND: p53 is the most commonly mutated tumour-suppressor gene in human cancers. Unlike other tumour-suppressor genes, most p53 cancer mutations are missense mutations within the core domain, leading to the expression of a full-length mutant p53 protein. Accumulating evidence has indicated that...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778523/ https://ncbi.nlm.nih.gov/pubmed/19773755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605335 |
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