Kinetics of early TCR signaling regulate the pathway of lytic granule delivery to the secretory domain

Cytolytic granule mediated killing of virus-infected cells is an essential function of cytotoxic T lymphocytes. Analysis of lytic granule delivery shows that the granules can take long or short paths to the secretory domain where they are released. Both paths utilize the same intracellular molecular...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Beal, Allison M., Anikeeva, Nadia, Varma, Rajat, Cameron, Thomas O., Vasiliver-Shamis, Gaia, Norris, Philip J., Dustin, Michael L., Sykulev, Yuri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778196/
https://ncbi.nlm.nih.gov/pubmed/19833088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.09.004
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