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Role of the carbonyl group of the (6–4) photoproduct in the (6–4) photolyase reaction
The (6–4) photoproduct, which is one of the major UV-induced DNA lesions, causes carcinogenesis with high frequency. The (6–4) photolyase is a flavoprotein that can restore this lesion to the original bases, but its repair mechanism has not been elucidated. In this study, we focused on the interacti...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777982/ https://ncbi.nlm.nih.gov/pubmed/19715341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900956p |
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