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Structural role of two histidines in the (6-4) photolyase reaction
Photolyases (PHRs) are DNA repair enzymes that revert UV-induced photoproducts, either cyclobutane pyrimidine dimers (CPD) or (6-4) photoproducts (PPs), into normal bases to maintain genetic integrity. (6-4) PHR must catalyze not only covalent bond cleavage, but also hydroxyl or amino group transfer...
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| Publicado no: | Biophys Physicobiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society of Japan (BSJ)
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736838/ https://ncbi.nlm.nih.gov/pubmed/27493863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.12.0_139 |
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