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Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization
Haspin, a nuclear and chromosome-associated serine/threonine (S/T) kinase, is responsible for mitotic phosphorylation of Thr-3 of histone H3. Haspin bears recognizable similarity to the eukaryotic protein kinase (ePK) fold, but its sequence is highly divergent and there is therefore considerable int...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777964/ https://ncbi.nlm.nih.gov/pubmed/19918049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908485106 |
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