Redox modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac death

AIMS: Although cardiac alternans is a known predictor of lethal arrhythmias, its underlying causes remain largely undefined in disease settings. The potential role of, and mechanisms responsible for, beat-to-beat alternations in the amplitude of systolic Ca(2+) transients (Ca(2+) alternans) was inve...

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Main Authors: Belevych, Andriy E., Terentyev, Dmitry, Viatchenko-Karpinski, Serge, Terentyeva, Radmila, Sridhar, Arun, Nishijima, Yoshinori, Wilson, Lance D., Cardounel, Arturo J., Laurita, Kenneth R., Carnes, Cynthia A., Billman, George E., Gyorke, Sandor
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777950/
https://ncbi.nlm.nih.gov/pubmed/19617226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp246
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