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α-Synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics

The function of α-synuclein, a soluble protein abundant in the brain and concentrated at presynaptic terminals, is still undefined. Yet, α-synuclein overexpression and the expression of its A30P mutant are associated with familial Parkinson's disease. Working in cell-free conditions, in two cel...

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Autors principals: Sousa, Vítor L., Bellani, Serena, Giannandrea, Maila, Yousuf, Malikmohamed, Valtorta, Flavia, Meldolesi, Jacopo, Chieregatti, Evelina
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777932/
https://ncbi.nlm.nih.gov/pubmed/19553474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-03-0302
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