Mechanisms of Alpha-Synuclein Action on Neurotransmission: Cell-Autonomous and Non-Cell Autonomous Role

Mutations and duplication/triplication of the alpha-synuclein (αSyn)-coding gene have been found to cause familial Parkinson’s disease (PD), while genetic polymorphisms in the region controlling the expression level and stability of αSyn have been identified as risk factors for idiopathic PD, pointi...

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Detalhes bibliográficos
Main Authors: Marco Emanuele, Evelina Chieregatti
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2015-05-01
Colecção:Biomolecules
Assuntos:
alpha-synuclein
exo/endocytosis
calcium entry
non-cell autonomous
lipid microdomains
Acesso em linha:http://www.mdpi.com/2218-273X/5/2/865
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