Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

BACKGROUND: WR1065 is the free-thiol metabolite of the cytoprotective aminothiol amifostine, which is used clinically at very high doses to protect patients against toxicity induced by radiation and chemotherapy. In an earlier study we briefly reported that the aminothiol WR1065 also inhibits HIV-1...

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Bibliografske podrobnosti
Main Authors: Poirier, Miriam C, Olivero, Ofelia A, Hardy, Andrew W, Franchini, Genoveffa, Borojerdi, Jennifer P, Walker, Vernon E, Walker, Dale M, Shearer, Gene M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777914/
https://ncbi.nlm.nih.gov/pubmed/19895691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-6-24
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