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DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

Genes are not simply turned on or off, but instead their expression is fine-tuned to meet the needs of a cell. How genes are modulated so precisely is not well understood. The glucocorticoid receptor (GR) regulates target genes by associating with specific DNA binding sites, the sequences of which d...

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Autori principali: Meijsing, Sebastiaan H., Pufall, Miles A., So, Alex Y., Bates, Darren L., Chen, Lin, Yamamoto, Keith R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777810/
https://ncbi.nlm.nih.gov/pubmed/19372434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164265
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