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Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction

Despite recent advances in the design of hemoglobin (Hb)-based oxygen carriers (HBOCs), vasoconstriction, presumably caused by nitric oxide (NO) scavenging, vessel wall hyperoxygenation, and/or extravasation, has been identified as the principal road block hampering commercial development of HBOCs....

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Detalhes bibliográficos
Main Authors: Cabrales, Pedro, Sun, Guoyong, Zhou, Yipin, Harris, David R., Tsai, Amy G., Intaglietta, Marcos, Palmer, Andre F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777796/
https://ncbi.nlm.nih.gov/pubmed/19745190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00622.2009
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