Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis

The release of reactive oxygen species (ROS) and cytokines by alveolar macrophages has been demonstrated in asbestos-induced pulmonary fibrosis, but the mechanism linking alveolar macrophages to the pathogenesis is not known. The GTPase Rac1 is a second messenger that plays an important role in host...

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Main Authors: Murthy, Shubha, Adamcakova-Dodd, Andrea, Perry, Sarah S., Tephly, Linda A., Keller, Richard M., Metwali, Nervana, Meyerholz, David K., Wang, Yongqiang, Glogauer, Michael, Thorne, Peter S., Carter, A. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777495/
https://ncbi.nlm.nih.gov/pubmed/19684199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90590.2008
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