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Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides

Here it is demonstrated that the yeast Saccharomyces cerevisiae can take up and assemble at least 38 overlapping single-stranded oligonucleotides and a linear double-stranded vector in one transformation event. These oligonucleotides can overlap by as few as 20 bp, and can be as long as 200 nucleoti...

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Detalles Bibliográficos
Autor Principal: Gibson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777417/
https://ncbi.nlm.nih.gov/pubmed/19745056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp687
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