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Generation and Characterization of Mice Carrying a Conditional Allele of the Wwox Tumor Suppressor Gene
WWOX, the gene that spans the second most common human chromosomal fragile site, FRA16D, is inactivated in multiple human cancers and behaves as a suppressor of tumor growth. Since we are interested in understanding WWOX function in both normal and cancer tissues we generated mice harboring a condit...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777388/ https://ncbi.nlm.nih.gov/pubmed/19936220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007775 |
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