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Wwox Hypomorphic Mice Display a Higher Incidence of B-Cell Lymphomas and Develop Testicular Atrophy
WWOX is a putative tumor suppressor gene encoded within common chromosomal fragile site region FRA16D, in chromo-some band 16q23. Multiple studies have demonstrated that WWOX expression is often reduced or lost in various tumor types. WWOX tumor suppressor activity was suggested by re-expressing WWO...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143238/ https://ncbi.nlm.nih.gov/pubmed/17823927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20497 |
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