Protective Role of R-spondin1, an Intestinal Stem Cell Growth Factor, against Radiation-Induced Gastrointestinal Syndrome in Mice

BACKGROUND: Radiation-induced gastrointestinal syndrome (RIGS) results from a combination of direct cytocidal effects on intestinal crypt and endothelial cells and subsequent loss of the mucosal barrier, resulting in electrolyte imbalance, diarrhea, weight loss, infection and mortality. Because R-sp...

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Bibliographische Detailangaben
Hauptverfasser: Bhanja, Payel, Saha, Subhrajit, Kabarriti, Rafi, Liu, Laibin, Roy-Chowdhury, Namita, Roy-Chowdhury, Jayanta, Sellers, Rani S., Alfieri, Alan A., Guha, Chandan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777375/
https://ncbi.nlm.nih.gov/pubmed/19956666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008014
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