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BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury

BACKGROUND: Radiation-induced gastrointestinal syndrome (RIGS) results from the acute loss of intestinal stem cells (ISC), impaired epithelial regeneration, and subsequent loss of the mucosal barrier, resulting in electrolyte imbalance, diarrhea, weight loss, sepsis, and mortality. The high radiosen...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Bhanja, Payel, Norris, Andrew, Gupta-Saraf, Pooja, Hoover, Andrew, Saha, Subhrajit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797353/
https://ncbi.nlm.nih.gov/pubmed/29394953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0763-3
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