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Mobilisation of Ca(2+) stores and flagellar regulation in human sperm by S-nitrosylation: a role for NO synthesised in the female tract

Generation of NO by nitric oxide synthase (NOS) is implicated in gamete interaction and fertilisation. Exposure of human spermatozoa to NO donors caused mobilisation of stored Ca(2+) by a mechanism that did not require activation of guanylate cyclase but was mimicked by S-nitroso-glutathione (GSNO;...

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Main Authors: Machado-Oliveira, Gisela, Lefièvre, Linda, Ford, Christopher, Herrero, M Belen, Barratt, Christopher, Connolly, Thomas J, Nash, Katherine, Morales-Garcia, Aduen, Kirkman-Brown, Jackson, Publicover, Steve
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777309/
https://ncbi.nlm.nih.gov/pubmed/18842814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.024521
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