Human Spermatozoa Contain Multiple Targets for Protein S-Nitrosylation: An Alternative Mechanism of the Modulation of Sperm Function by Nitric Oxide?

Nitric oxide (NO) enhances human sperm motility and capacitation associated with increased protein phosphorylation. NO activates soluble guanylyl cyclase, but can also modify protein function covalently via S-nitrosylation of cysteine. Remarkably, this mechanism remains unexplored in sperm although...

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Autori principali: Lefièvre, Linda, Chen, Yongjian, Conner, Sarah J, Scott, Joanna L, Publicover, Steve J, Ford, W Christopher L, Barratt, Christopher LR
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777308/
https://ncbi.nlm.nih.gov/pubmed/17683036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200700254
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