Polymorphisms in glutathione S-transferase genes increase risk of prostate cancer biochemical recurrence differentially by ethnicity and disease severity

OBJECTIVE: Genetic polymorphisms that modify the detoxifying activity of glutathione S-transferases (GSTs) can affect the level of carcinogenic metabolites created by endogenous steroid hormones and exogenous chemical substances. Although the GSTM1 null genotype has been shown to increase prostate c...

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Bibliographische Detailangaben
Hauptverfasser: Nock, Nora L., Bock, Cathryn, Neslund-Dudas, Christine, Beebe-Dimmer, Jennifer, Rundle, Andrew, Tang, Deliang, Jankowski, Michelle, Rybicki, Benjamin A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2009
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777237/
https://ncbi.nlm.nih.gov/pubmed/19568698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-009-9385-0
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