SRD5A2 and HSD3B2 Polymorphisms are Associated With Prostate Cancer Risk and Aggressiveness

BACKGROUND: Dihydrotestosterone (DHT) is believed to play an important role in prostate carcinogenesis. Five alpha reductase type II (SRD5A2) and 3 beta-hydroxysteroid dehydrogenase type II (HSD3B2) are responsible for the biosynthesis and degradation of DHT in the prostate. Two polymorphisms, a val...

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Bibliografiset tiedot
Päätekijät: Neslund-Dudas, Christine, Bock, Cathryn H., Monaghan, Kristin, Nock, Nora L., Yang, James J., Rundle, Andrew, Tang, Deliang, Rybicki, Benjamin A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132439/
https://ncbi.nlm.nih.gov/pubmed/17823934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20625
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