Associations between Smoking, Polymorphisms in Polycyclic Aromatic Hydrocarbon (PAH) Metabolism and Conjugation Genes and PAH-DNA Adducts in Prostate Tumors Differ by Race

Polycyclic aromatic hydrocarbon (PAH)-DNA adducts may induce mutations that contribute to carcinogenesis. We evaluated potential associations between smoking and polymorphisms in PAH metabolism [CYP1A1 Ile(462)Val, CYP1B1 Ala(119)Ser and Leu(432)Val, microsomal epoxide hydrolase (mEH) Tyr(113)His an...

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Main Authors: Nock, Nora L., Tang, Deliang, Rundle, Andrew, Neslund-Dudas, Christine, Savera, Adnan T., Bock, Cathryn H., Monaghan, Kristin G., Koprowski, Allison, Mitrache, Nicoleta, Yang, James J., Rybicki, Benjamin A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151314/
https://ncbi.nlm.nih.gov/pubmed/17548691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-06-0736
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