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Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi

Glutathione transferases are a multigene family of proteins that catalyze the conjugation of toxic electrophiles and carcinogens to glutathione. Glutathione transferase Pi (GSTP) is commonly overexpressed in human tumors and there is emerging evidence that the enzyme has additional cellular function...

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Autores principales: Ritchie, Kenneth J., Walsh, Shaun, Sansom, Owen J., Henderson, Colin J., Wolf, C. Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777186/
https://ncbi.nlm.nih.gov/pubmed/19915149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911351106
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