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Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases

The activity of chemical carcinogens is a complex balance between metabolic activation by cytochrome P450 monooxygenases and detoxification by enzymes such as glutathione S-transferase (GST). Regulation of these proteins may have profound effects on carcinogenic activity, although it has proved impo...

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Detalhes bibliográficos
Main Authors: Henderson, Colin J., Smith, Austin G., Ure, Jan, Brown, Ken, Bacon, E. Jane, Wolf, C. Roland
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20251/
https://ncbi.nlm.nih.gov/pubmed/9560266
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