Developmental Exposure to Manganese Increases Adult Susceptibility to Inflammatory Activation of Glia and Neuronal Protein Nitration

Chronic exposure to manganese (Mn) produces a neurodegenerative disorder affecting the basal ganglia characterized by reactive gliosis and expression of neuroinflammatory genes including inducible nitric oxide synthase (NOS2). Induction of NOS2 in glial cells causes overproduction of nitric oxide (N...

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Detaylı Bibliyografya
Asıl Yazarlar: Moreno, Julie A., Streifel, Karin M., Sullivan, Kelly A., Legare, Marie E., Tjalkens, Ronald B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Neurotoxicology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777079/
https://ncbi.nlm.nih.gov/pubmed/19812365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp221
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