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Purification, crystallization and preliminary X-ray analysis of bifunctional isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli
Escherichia coli isocitrate dehydrogenase (ICDH) can be phosphorylated and dephosphorylated by a single bifunctional protein, isocitrate dehydrogenase kinase/phosphatase (AceK), which is encoded by the aceK gene. In order to investigate the regulatory mechanism of (de)phosphorylation of ICDH by AceK...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777047/ https://ncbi.nlm.nih.gov/pubmed/19923739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109038718 |
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