Structure of an Escherichia coli N-acetyl-d-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 Å resolution

The structure of a mutant variant of Escherichia coli N-acetyl-d-neuraminic acid lyase (NAL), E192N, in complex with pyruvate has been determined in a new crystal form. It crystallized in space group P2(1)2(1)2(1), with unit-cell parameters a = 78.3, b = 108.5, c = 148.3 Å. Pyruvate has been trapped...

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Autores principales: Campeotto, Ivan, Carr, Stephen B., Trinh, Chi H., Nelson, Adam S., Berry, Alan, Phillips, Simon E. V., Pearson, Arwen R.
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2009
Materias:
Structural Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777032/
https://ncbi.nlm.nih.gov/pubmed/19923724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109037403
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