Frequent Long-Range Epigenetic Silencing of Protocadherin Gene Clusters on Chromosome 5q31 in Wilms' Tumor

Wilms' tumour (WT) is a pediatric tumor of the kidney that arises via failure of the fetal developmental program. The absence of identifiable mutations in the majority of WTs suggests the frequent involvement of epigenetic aberrations in WT. We therefore conducted a genome-wide analysis of prom...

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Main Authors: Dallosso, Anthony R., Hancock, Anne L., Szemes, Marianna, Moorwood, Kim, Chilukamarri, Laxmi, Tsai, Hsin-Hao, Sarkar, Abby, Barasch, Jonathan, Vuononvirta, Raisa, Jones, Chris, Pritchard-Jones, Kathy, Royer-Pokora, Brigitte, Lee, Sean Bong, Owen, Ceris, Malik, Sally, Feng, Yi, Frank, Marcus, Ward, Andrew, Brown, Keith W., Malik, Karim
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776977/
https://ncbi.nlm.nih.gov/pubmed/19956686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000745
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