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Insights into the anthrax lethal factor–substrate interaction and selectivity using docking and molecular dynamics simulations
The anthrax toxin of the bacterium Bacillus anthracis consists of three distinct proteins, one of which is the anthrax lethal factor (LF). LF is a gluzincin Zn-dependent, highly specific metalloprotease with a molecular mass of ∼90 kDa that cleaves most isoforms of the family of mitogen-activated pr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776964/ https://ncbi.nlm.nih.gov/pubmed/19585464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.169 |
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