Molecular Docking Simulations Provide Insights in the Substrate Binding Sites and Possible Substrates of the ABCC6 Transporter

The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein (ABCC6), primarily expressed in liver and kidney. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum (PXE), an autosomal recessive connective tissue disease characterized by ectopic mineralizatio...

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Bibliographic Details
Main Authors: Hosen, Mohammad Jakir, Zubaer, Abdullah, Thapa, Simrika, Khadka, Bijendra, De Paepe, Anne, Vanakker, Olivier M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111409/
https://ncbi.nlm.nih.gov/pubmed/25062064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102779
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