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Molecular Docking Simulations Provide Insights in the Substrate Binding Sites and Possible Substrates of the ABCC6 Transporter

The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein (ABCC6), primarily expressed in liver and kidney. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum (PXE), an autosomal recessive connective tissue disease characterized by ectopic mineralizatio...

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Библиографические подробности
Главные авторы: Hosen, Mohammad Jakir, Zubaer, Abdullah, Thapa, Simrika, Khadka, Bijendra, De Paepe, Anne, Vanakker, Olivier M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111409/
https://ncbi.nlm.nih.gov/pubmed/25062064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102779
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