An Evolutionary Model-Based Algorithm for Accurate Phylogenetic Breakpoint Mapping and Subtype Prediction in HIV-1

Genetically diverse pathogens (such as Human Immunodeficiency virus type 1, HIV-1) are frequently stratified into phylogenetically or immunologically defined subtypes for classification purposes. Computational identification of such subtypes is helpful in surveillance, epidemiological analysis and d...

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Hauptverfasser: Kosakovsky Pond, Sergei L., Posada, David, Stawiski, Eric, Chappey, Colombe, Poon, Art F.Y., Hughes, Gareth, Fearnhill, Esther, Gravenor, Mike B., Leigh Brown, Andrew J., Frost, Simon D.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776870/
https://ncbi.nlm.nih.gov/pubmed/19956739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000581
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