A Conserved CXXC Motif in CD3ε Is Critical for T Cell Development and TCR Signaling

Virtually all T cell development and functions depend on its antigen receptor. The T cell receptor (TCR) is a multi-protein complex, comprised of a ligand binding module and a signal transmission module. The signal transmission module includes proteins from CD3 family (CD3ε, CD3δ, CD3γ) as well as t...

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Bibliografiske detaljer
Main Authors: Wang, Yibing, Becker, Dean, Vass, Tibor, White, Janice, Marrack, Philippa, Kappler, John W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776832/
https://ncbi.nlm.nih.gov/pubmed/19956738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000253
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