Aldehyde Dehydrogenase Expressing Colon Stem Cells Contribute to Tumorigenesis in the Transition from Colitis to Cancer

Patients with chronic ulcerative colitis are at increased risk of developing colorectal cancer. Though current hypotheses suggest that sporadic colorectal cancer is due to inability to control cancer stem cells, the cancer stem cell hypothesis has not yet been validated in colitis-associated cancer....

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Main Authors: Carpentino, Joseph E., Hynes, Mark J., Appelman, Henry D., Zheng, Tong, Steindler, Dennis A., Scott, Edward W., Huang, Emina H.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776663/
https://ncbi.nlm.nih.gov/pubmed/19808966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1132
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