Transition From Colitis to Cancer: High Wnt Activity Sustains The Tumor-Initiating Potential Of Colon Cancer Stem Cell Precursors

Ulcerative colitis (UC) increases the risk of colorectal cancer (CRC), but the mechanisms involved in colitis-to-cancer transition (CCT) are not well understood. CCT may involve a inflammation-dysplasia-carcinoma progression sequence compared to the better characterized adenoma-carcinoma progression...

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Detalhes bibliográficos
Main Authors: Shenoy, Anitha K., Fisher, Robert C., Butterworth, Elizabeth A., Pi, Liya, Chang, Lung-Ji, Appelman, Henry D., Chang, Myron, Scott, Edward W., Huang, Emina H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463774/
https://ncbi.nlm.nih.gov/pubmed/22902411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1806
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