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REPLICATIVE POTENTIAL OF HUMAN NATURAL KILLER CELLS

The replicative potential of human CD56(+) CD3(−) natural killer (NK) cells is unknown. We found that by exposing NK cells to the leukemic cell line K562 genetically modified to express 4-1BB ligand and interleukin 15 (K562-mb15-41BBL), they expanded for up to 30 population doublings, achieving numb...

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Detalhes bibliográficos
Main Authors: Fujisaki, Hiroyuki, Kakuda, Harumi, Imai, Chihaya, Mullighan, Charles G., Campana, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776622/
https://ncbi.nlm.nih.gov/pubmed/19344420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07667.x
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