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CYTOTOXICITY OF ACTIVATED NATURAL KILLER CELLS AGAINST PEDIATRIC SOLID TUMORS

PURPOSE: To develop new therapies for children with solid tumors, we tested the cytotoxicity of natural killer (NK) cells expanded by coculture with K562-mb15-41BBL cells. We sought to identify the most sensitive tumor subtypes, clarify the molecular interactions regulating cytotoxicity, and determi...

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Detalhes bibliográficos
Main Authors: Cho, Duck, Shook, David R., Shimasaki, Noriko, Chang, Yu-Hsiang, Fujisaki, Hiroyuki, Campana, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168562/
https://ncbi.nlm.nih.gov/pubmed/20542985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0735
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