Cohesin Is Required for Higher-Order Chromatin Conformation at the Imprinted IGF2-H19 Locus

Cohesin is a chromatin-associated protein complex that mediates sister chromatid cohesion by connecting replicated DNA molecules. Cohesin also has important roles in gene regulation, but the mechanistic basis of this function is poorly understood. In mammalian genomes, cohesin co-localizes with CCCT...

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Autors principals: Nativio, Raffaella, Wendt, Kerstin S., Ito, Yoko, Huddleston, Joanna E., Uribe-Lewis, Santiago, Woodfine, Kathryn, Krueger, Christel, Reik, Wolf, Peters, Jan-Michael, Murrell, Adele
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776306/
https://ncbi.nlm.nih.gov/pubmed/19956766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000739
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