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Cohesin Is Required for Higher-Order Chromatin Conformation at the Imprinted IGF2-H19 Locus

Cohesin is a chromatin-associated protein complex that mediates sister chromatid cohesion by connecting replicated DNA molecules. Cohesin also has important roles in gene regulation, but the mechanistic basis of this function is poorly understood. In mammalian genomes, cohesin co-localizes with CCCT...

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Bibliografische gegevens
Hoofdauteurs: Nativio, Raffaella, Wendt, Kerstin S., Ito, Yoko, Huddleston, Joanna E., Uribe-Lewis, Santiago, Woodfine, Kathryn, Krueger, Christel, Reik, Wolf, Peters, Jan-Michael, Murrell, Adele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776306/
https://ncbi.nlm.nih.gov/pubmed/19956766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000739
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