Cohesin Is Required for Higher-Order Chromatin Conformation at the Imprinted IGF2-H19 Locus

Cohesin is a chromatin-associated protein complex that mediates sister chromatid cohesion by connecting replicated DNA molecules. Cohesin also has important roles in gene regulation, but the mechanistic basis of this function is poorly understood. In mammalian genomes, cohesin co-localizes with CCCT...

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Main Authors: Nativio, Raffaella, Wendt, Kerstin S., Ito, Yoko, Huddleston, Joanna E., Uribe-Lewis, Santiago, Woodfine, Kathryn, Krueger, Christel, Reik, Wolf, Peters, Jan-Michael, Murrell, Adele
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776306/
https://ncbi.nlm.nih.gov/pubmed/19956766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000739
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