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Anthropomorphizing the Mouse Cardiac Action Potential via a Novel Dynamic Clamp Method

Interspecies differences can limit the translational value of excitable cells isolated from model organisms. It can be difficult to extrapolate from a drug- or mutation-induced phenotype in mice to human pathophysiology because mouse and human cardiac electrodynamics differ greatly. We present a hyb...

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Bibliografiske detaljer
Main Authors: Ahrens-Nicklas, Rebecca C., Christini, David J.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776258/
https://ncbi.nlm.nih.gov/pubmed/19917221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.002
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