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A murine model of myeloma that allows genetic manipulation of the host microenvironment

Multiple myeloma, and the associated osteolytic bone disease, is highly dependent upon cellular interactions within the bone marrow microenvironment. A major limitation of existing myeloma models is the requirement for a specific host strain of mouse, preventing molecular examination of the bone mar...

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Detalles Bibliográficos
Main Authors: Fowler, Jessica A., Mundy, Gregory R., Lwin, Seint T., Lynch, Conor C., Edwards, Claire M.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Limited 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776114/
https://ncbi.nlm.nih.gov/pubmed/19779066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003160
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