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A murine model of myeloma that allows genetic manipulation of the host microenvironment

Multiple myeloma, and the associated osteolytic bone disease, is highly dependent upon cellular interactions within the bone marrow microenvironment. A major limitation of existing myeloma models is the requirement for a specific host strain of mouse, preventing molecular examination of the bone mar...

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Autors principals: Fowler, Jessica A., Mundy, Gregory R., Lwin, Seint T., Lynch, Conor C., Edwards, Claire M.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776114/
https://ncbi.nlm.nih.gov/pubmed/19779066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003160
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